This book gives an overview regarding mental health and quality of life issues across the life span within the interdisciplinary field of transgender healthcare. Originally published as a special issue of the International Review of Psychiatry. Table of Contents: Introduction: Gender Dysphoria and Gender Incongruence: An evolving inter-disciplinary field1. Gender incongruence/gender dysphoria and its classification history 2. Gender dysphoria in childhood 3. Gender dysphoria in adolescence 4. Families in transition: A literature review 5. Mental health and gender dysphoria: A review of the literature 6. Non-suicidal self-injury and suicidality in trans people: A systematic review of the literature 7. Gender dysphoria and autism spectrum disorder: A narrative review 8. Body dissatisfaction and disordered eating in trans people: A systematic review of the literature 9. Non-binary or genderqueer genders 10. Sexual orientation of trans adults is not linked to outcome of transition-related health care, but worth asking 11. Fertility options in transgender people 12. Neuroimaging studies in people with gender incongruence.